Brief research report: Transcriptional blockade of angiotensin converting enzyme 2 modelled in human retinal pigment epithelial cells

Brief research report: Transcriptional blockade of angiotensin converting enzyme 2 modelled in human retinal pigment epithelial cells

As a key host protein involved in cellular infection by the severe acute respiratory syndrome coronavirus (SARS-CoV-2), angiotensin converting enzyme (ACE)2 is an ideal target for antiviral drugs. Manipulation of transcription provides opportunity for graduated blockade that preserves physiological...

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Main Authors: Liam M. Ashander (Author), Amanda L. Lumsden (Author), Yuefang Ma (Author), Alwin Chun Rong Tan (Author), Binoy Appukuttan (Author), Santhosh Daniel (Author), Michael Z. Michael (Author), Justine R. Smith (Author)
Format: Book
Published: Frontiers Media S.A., 2024-10-01T00:00:00Z.
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