Gene expression profile of ABC transporters and cytotoxic effect of ibuprofen and acetaminophen in an epithelial ovarian cancer cell line in vitro

• Main Authors: Renilton Aires Lima (Author), Eduardo Batista Cândido (Author), Flávia Perrim de Melo (Author), Josiane Barbosa Piedade (Author), Paula Vieira Teixeira Vidigal (Author), Luciana Maria Silva (Author), Agnaldo Lopes da Silva Filho (Author)
• Format: Book
• Published: Federação Brasileira das Sociedades de Ginecologia e Obstetrícia, 2015-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

PURPOSES: To determine the basic expression of ABC transporters in an epithelial ovarian cancer cell line, and to investigate whether low concentrations of acetaminophen and ibuprofen inhibited the growth of this cell line in vitro. METHODS: TOV-21 G cells were exposed to different concentrations of...