OncomiR miR-182-5p Enhances Radiosensitivity by Inhibiting the Radiation-Induced Antioxidant Effect through SESN2 in Head and Neck Cancer

• Main Authors: Min-Ying Lin (Author), Yu-Chan Chang (Author), Shan-Ying Wang (Author), Muh-Hwa Yang (Author), Chih-Hsien Chang (Author), Michael Hsiao (Author), Richard N. Kitsis (Author), Yi-Jang Lee (Author)
• Format: Book
• Published: MDPI AG, 2021-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Radiotherapy is routinely used for the treatment of head and neck squamous cell carcinoma (HNSCC). However, the therapeutic efficacy is usually reduced by acquired radioresistance and locoregional recurrence. In this study, The Cancer Genome Atlas (TCGA) analysis showed that radiotherapy upregulated...