Non-Mammalian Prdx6 Enzymes (Proteins with 1-Cys Prdx Mechanism) Display PLA2 Activity Similar to the Human Orthologue

• 主要な著者: Renata Bannitz-Fernandes (著者), Rogério Aleixo-Silva (著者), João Paulo Silva (著者), Chandra Dodia (著者), Jose Pablo Vazquez-Medina (著者), Jian-Qin Tao (著者), Aron Fisher (著者), Luis Netto (著者)
• フォーマット: 図書
• 出版事項: MDPI AG, 2019-03-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Mammalian peroxiredoxin class 6 (Prdx6) are bifunctional enzymes. Non-mammalian Prdx6 enzymes display Cys-based peroxidase activity, but to date their putative phospholipase A2 (PLA2 activities) has not been experimentally investigated. Initially, we observed that five non-mammalian Prdx6 enzymes (e...