Non-Mammalian Prdx6 Enzymes (Proteins with 1-Cys Prdx Mechanism) Display PLA2 Activity Similar to the Human Orthologue

• Prif Awduron: Renata Bannitz-Fernandes (Awdur), Rogério Aleixo-Silva (Awdur), João Paulo Silva (Awdur), Chandra Dodia (Awdur), Jose Pablo Vazquez-Medina (Awdur), Jian-Qin Tao (Awdur), Aron Fisher (Awdur), Luis Netto (Awdur)
• Fformat: Llyfr
• Cyhoeddwyd: MDPI AG, 2019-03-01T00:00:00Z.
• Pynciau: article
• Mynediad Ar-lein: Connect to this object online.

Mammalian peroxiredoxin class 6 (Prdx6) are bifunctional enzymes. Non-mammalian Prdx6 enzymes display Cys-based peroxidase activity, but to date their putative phospholipase A2 (PLA2 activities) has not been experimentally investigated. Initially, we observed that five non-mammalian Prdx6 enzymes (e...