Grindelia squarrosa Extract and Grindelic Acid Modulate Pro-inflammatory Functions of Respiratory Epithelium and Human Macrophages

• Glavni autori: Barbara Gierlikowska (Autor), Agnieszka Filipek (Autor), Wojciech Gierlikowski (Autor), Dominika Kania (Autor), Joanna Stefańska (Autor), Urszula Demkow (Autor), Anna K. Kiss (Autor)
• Format: Knjiga
• Izdano: Frontiers Media S.A., 2021-01-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

Aim of the study: Both nasal and bronchial epithelial cells have evolved sophisticated mechanisms involved in cellular response to bacterial infection. Recognition of pathogens by TLR receptors activate the NF-κB transcription factor, and lead to production of wide spectrum of cytokines (TNF-α, IL-1...