Crovirin, a snake venom cysteine-rich secretory protein (CRISP) with promising activity against Trypanosomes and Leishmania.

• Main Authors: Camila M Adade (Author), Ana Lúcia O Carvalho (Author), Marcelo A Tomaz (Author), Tatiana F R Costa (Author), Joseane L Godinho (Author), Paulo A Melo (Author), Ana Paula C A Lima (Author), Juliany C F Rodrigues (Author), Russolina B Zingali (Author), Thaïs Souto-Padrón (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2014-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The neglected human diseases caused by trypanosomatids are currently treated with toxic therapy with limited efficacy. In search for novel anti-trypanosomatid agents, we showed previously that the Crotalus viridis viridis (Cvv) snake venom was active against infective forms of Trypanosoma cruzi. Her...