Downregulation of PI3K/AKT/mTOR Pathway in Juglone-Treated Bovine Oocytes

• Main Authors: Marwa El-Sheikh (Author), Ayman Mesalam (Author), Atif Ali Khan Khalil (Author), Muhammad Idrees (Author), Mi-Jeong Ahn (Author), Ahmed Atef Mesalam (Author), Il-Keun Kong (Author)
• Format: Book
• Published: MDPI AG, 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

We have previously reported that juglone, a natural compound found in Juglandaceae with a wide range of biological activities, can reduces the developmental competence of bovine oocytes. In the current study, we investigated the possible mechanisms behind the toxicity of juglone and the relationship...