Comprehensive analysis of FRAS1/FREM family as potential biomarkers and therapeutic targets in renal clear cell carcinoma

• Main Authors: Ganggang Wang (Author), Zheng Wang (Author), Haiquan Lu (Author), Zhiqun Zhao (Author), Liqiang Guo (Author), Feng Kong (Author), Aizhen Wang (Author), Shengtian Zhao (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: FRAS1 (Fraser syndrome protein 1), together with FREM1 (the Fras1-related extracellular matrix proteins 1) and FREM2, belonging to the FRAS1/FREM extracellular matrix protein family, are considered to play essential roles in renal organogenesis and cancer progression. However, their role...