Quality assessment of a clinical next-generation sequencing melanoma panel within the Italian Melanoma Intergroup (IMI)

• Main Authors: Irene Vanni (Author), Milena Casula (Author), Lorenza Pastorino (Author), Antonella Manca (Author), Bruna Dalmasso (Author), Virginia Andreotti (Author), Marina Pisano (Author), Maria Colombino (Author), Italian Association for Cancer Research (AIRC) (Author), Ulrich Pfeffer (Author), Enrica Teresa Tanda (Author), Carla Rozzo (Author), Panagiotis Paliogiannis (Author), Antonio Cossu (Author), Paola Ghiorzo (Author), Giuseppe Palmieri (Author), for the Italian Melanoma Intergroup (IMI) (Author)
• Format: Book
• Published: BMC, 2020-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Identification of somatic mutations in key oncogenes in melanoma is important to lead the effective and efficient use of personalized anticancer treatment. Conventional methods focus on few genes per run and, therefore, are unable to screen for multiple genes simultaneously. The...