Leishmania major infection in humanized mice induces systemic infection and provokes a nonprotective human immune response.

• প্রধান লেখক: Anja Kathrin Wege (লেখক), Christian Florian (লেখক), Wolfgang Ernst (লেখক), Nicole Zimara (লেখক), Ulrike Schleicher (লেখক), Frank Hanses (লেখক), Maximilian Schmid (লেখক), Uwe Ritter (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Public Library of Science (PLoS), 2012-01-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

BACKGROUND: Leishmania (L.) species are the causative agent of leishmaniasis. Due to the lack of efficient vaccine candidates, drug therapies are the only option to deal with cutaneous leishmaniasis. Unfortunately, chemotherapeutic interventions show high toxicity in addition to an increased risk of...