K+-Channel Openers Suppress Epileptiform Activities Induced by 4-Aminopyridine in Cultured Rat Hippocampal Neurons

K+ channels are key modulators of neuronal excitability, and mutations in certain types of these channels are known to cause epileptic seizures. Activation of K+ channels is reported to suppress epileptic discharge; however, the types of K+-channel openers that are most effective as anti-epileptic a...

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Auteurs principaux: Kiyoaki Kobayashi (Auteur), Yukio Nishizawa (Auteur), Kohei Sawada (Auteur), Hiroo Ogura (Auteur), Masayuki Miyabe (Auteur)
Format: Livre
Publié: Elsevier, 2008-01-01T00:00:00Z.
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