H. pylori virulence factor CagA increases intestinal cell proliferation by Wnt pathway activation in a transgenic zebrafish model

• Asıl Yazarlar: James T. Neal (Yazar), Tracy S. Peterson (Yazar), Michael L. Kent (Yazar), Karen Guillemin (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: The Company of Biologists, 2013-05-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

SUMMARY Infection with Helicobacter pylori is a major risk factor for the development of gastric cancer, and infection with strains carrying the virulence factor CagA significantly increases this risk. To investigate the mechanisms by which CagA promotes carcinogenesis, we generated transgenic zebra...