Data-driven prediction of adverse drug reactions induced by drug-drug interactions

• Главные авторы: Ruifeng Liu (Автор), Mohamed Diwan M. AbdulHameed (Автор), Kamal Kumar (Автор), Xueping Yu (Автор), Anders Wallqvist (Автор), Jaques Reifman (Автор)
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• Опубликовано: BMC, 2017-06-01T00:00:00Z.
• Предметы: article
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Abstract Background The expanded use of multiple drugs has increased the occurrence of adverse drug reactions (ADRs) induced by drug-drug interactions (DDIs). However, such reactions are typically not observed in clinical drug-development studies because most of them focus on single-drug therapies....