The effect of frailty on HAI response to influenza vaccine among community-dwelling adults ≥ 50 years of age

• Main Authors: Krissy K. Moehling (Author), Mary Patricia Nowalk (Author), Chyongchiou Jeng Lin (Author), Marnie Bertolet (Author), Ted M. Ross (Author), Chalise E. Carter (Author), Michael Susick (Author), Sean G. Saul (Author), A. Murat Kaynar (Author), Joyce T. Bromberger (Author), Richard K. Zimmerman (Author)
• Format: Book
• Published: Taylor & Francis Group, 2018-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The immune response to vaccine antigens is less robust in older adults because of changes in the aging immune system. Frailty, the multi-dimensional syndrome marked by losses in function and physiological reserve, is increasingly prevalent with advancing age. Frailty accelerates this immunosenescenc...