Allspice and Clove As Source of Triterpene Acids Activating the G Protein-Coupled Bile Acid Receptor TGR5

• Main Authors: Angela Ladurner (Author), Martin Zehl (Author), Ulrike Grienke (Author), Christoph Hofstadler (Author), Nadina Faur (Author), Fátima C. Pereira (Author), David Berry (Author), Verena M. Dirsch (Author), Judith M. Rollinger (Author)
• Format: Book
• Published: Frontiers Media S.A., 2017-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Worldwide, metabolic diseases such as obesity and type 2 diabetes have reached epidemic proportions. A major regulator of metabolic processes that gained interest in recent years is the bile acid receptor TGR5 (Takeda G protein-coupled receptor 5). This G protein-coupled membrane receptor can be fou...