Treponema pallidum Tp0751 alters the expression of tight junction proteins by promoting bEnd3 cell apoptosis and IL-6 secretion

• Main Authors: Simin Lu (Author), Jianye Wang (Author), Zhangping He (Author), Siqin He (Author), Kang Zheng (Author), Man Xu (Author), Shuai Yuan (Author), Yimou Wu (Author)
• Format: Book
• Published: Elsevier, 2022-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Neurosyphilis is a serious complication caused by the invasion of the central nervous system by Treponema pallidum subsp. pallidum (T. pallidum). However, the molecular mechanism by which T. pallidum crosses the blood-brain barrier has not been fully elucidated. Objectives: The primary p...