Liver hyperplasia after tamoxifen induction of Myc in a transgenic medaka model

• Main Authors: Luciana A. Menescal (Author), Cornelia Schmidt (Author), Daniel Liedtke (Author), Manfred Schartl (Author)
• Formato: Libro
• Publicado: The Company of Biologists, 2012-07-01T00:00:00Z.
• Subjects: article
• Acceso en liña: Connect to this object online.

SUMMARY Myc is a global transcriptional regulator and one of the most frequently overexpressed oncoproteins in human tumors. It is well established that activation of Myc leads to enhanced cell proliferation but can also lead to increased apoptosis. The use of animal models expressing deregulated le...