Anti-TNFα in inflammatory bowel disease: from originators to biosimilars

• Main Authors: Zhen Zeng (Author), Hao Lin (Author), Mingshan Jiang (Author), Jing Yuan (Author), Xi Li (Author), Yongbin Jia (Author), Li Yang (Author), Hu Zhang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The introduction of anti-tumor necrosis factor α (TNFα) biologics significantly innovated inflammatory bowel disease (IBD) treatment and increased medical costs. The recent expiration of patents of some anti-TNFα biologics (such as infliximab and adalimumab) facilitated the development of biosimilar...