The Ca2+ Channel Iinhibitor NNC 55-0396 Inhibits Voltage-Dependent K+ Channels in Rabbit Coronary Arterial Smooth Muscle Cells

• Main Authors: Youn Kyoung Son (Author), Da Hye Hong (Author), Hongliang Li (Author), Dae-Joong Kim (Author), Sung Hun Na (Author), Hongzoo Park (Author), Won-Kyo Jung (Author), Il-Whan Choi (Author), Won Sun Park (Author)
• Format: Book
• Published: Elsevier, 2014-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract.: We demonstrated the inhibitory effect of NNC 55-0396, a T-type Ca2+ channel inhibitor, on voltage-dependent K+ (KV) channels in freshly isolated rabbit coronary arterial smooth muscle cells. NNC 55-0396 decreased the amplitude of KV currents in a concentration-dependent manner, with an IC...