HPLC-MS and HPLC-MS/MS analysis of seven active constituents of Xiao-Xu-Ming decoction and application to a pharmacokinetic study after oral administration to rat

• Main Authors: Yilin Wang (Author), Chunguang Ding (Author), Caisheng Wu (Author), Kehe Du (Author), Jinlan Zhang (Author), Hailin Qin (Author), Jinfeng Hou (Author), Guanhua Du (Author)
• Format: Book
• Published: Elsevier, 2012-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Xiao-xu-ming decoction (XXMD) is a traditional Chinese medicine that has been widely used to treat theoplegia and its sequelae. This paper reports the development of three separate assays based on reversed phase high-performance liquid chromatography-mass spectrometry (HPLC-MS) and HPLC-MS/MS for th...