Modeling and study of the mechanism of dilated cardiomyopathy using induced pluripotent stem cells derived from individuals with Duchenne muscular dystrophy

• Main Authors: Bo Lin (Author), Yang Li (Author), Lu Han (Author), Aaron D. Kaplan (Author), Ying Ao (Author), Spandan Kalra (Author), Glenna C. L. Bett (Author), Randall L. Rasmusson (Author), Chris Denning (Author), Lei Yang (Author)
• Format: Book
• Published: The Company of Biologists, 2015-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Duchenne muscular dystrophy (DMD) is caused by mutations in the dystrophin gene (DMD), and is characterized by progressive weakness in skeletal and cardiac muscles. Currently, dilated cardiomyopathy due to cardiac muscle loss is one of the major causes of lethality in late-stage DMD patients. To stu...