Synthesis and Biological Evaluation of a Fused Structure of Indolizine and Pyrrolo[1,2-<i>c</i>]pyrimidine: Identification of Its Potent Anticancer Activity against Liver Cancer Cells

• Main Authors: Seonghyeon Nam (Author), Yechan Lee (Author), So-Hyeon Park (Author), Wan Namkung (Author), Ikyon Kim (Author)
• Format: Knjiga
• Izdano: MDPI AG, 2022-11-01T00:00:00Z.
• Teme: article
• Online dostop: Connect to this object online.

A highly efficient approach to a new indolizine scaffold fused with pyrrolo[1,2-<i>c</i>]pyrimidine was achieved via one-pot three-component coupling followed by an oxidative cyclization reaction. The simple two-step sequence allowed rapid access to various tetracyclic compounds from com...