AI‐based intra‐tumor heterogeneity score of Ki67 expression as a prognostic marker for early‐stage ER+/HER2− breast cancer

• Main Authors: Wenqi Lu (Author), Ayat G Lashen (Author), Noorul Wahab (Author), Islam M Miligy (Author), Mostafa Jahanifar (Author), Michael Toss (Author), Simon Graham (Author), Mohsin Bilal (Author), Abhir Bhalerao (Author), Nehal M Atallah (Author), Shorouk Makhlouf (Author), Asmaa Y Ibrahim (Author), David Snead (Author), Fayyaz Minhas (Author), Shan E Ahmed Raza (Author), Emad Rakha (Author), Nasir Rajpoot (Author)
• Format: Book
• Published: Wiley, 2024-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Early‐stage estrogen receptor positive and human epidermal growth factor receptor negative (ER+/HER2−) luminal breast cancer (BC) is quite heterogeneous and accounts for about 70% of all BCs. Ki67 is a proliferation marker that has a significant prognostic value in luminal BC despite the ch...