Cannabidiol, among other cannabinoid drugs, modulates prepulse inhibition of startle in the SHR animal model: implications for schizophrenia pharmacotherapy

• Main Authors: Fernanda Fiel Peres (Author), Raquel Levin (Author), Valéria Almeida (Author), Antonio Waldo Zuardi (Author), Jaime E Hallak (Author), José Alexandre Crippa (Author), Vanessa Costhek Abilio (Author)
• Format: Book
• Published: Frontiers Media S.A., 2016-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Schizophrenia is a severe psychiatric disorder that involves positive, negative and cognitive symptoms. Prepulse inhibition of startle reflex (PPI) is a paradigm that assesses the sensorimotor gating functioning and is impaired in schizophrenia patients as well as in animal models of this disorder....