Synthesis and bioactivities evaluation of oleanolic acid oxime ester derivatives as α-glucosidase and α-amylase inhibitors

• Váldodahkkit: Xu-Yang Deng (Dahkki), Jun-Jie Ke (Dahkki), Ying-Ying Zheng (Dahkki), Dong-Li Li (Dahkki), Kun Zhang (Dahkki), Xi Zheng (Dahkki), Jing-Ying Wu (Dahkki), Zhuang Xiong (Dahkki), Pan-Pan Wu (Dahkki), Xue-Tao Xu (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Taylor & Francis Group, 2022-12-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Different oleanolic acid (OA) oxime ester derivatives (3a-3t) were designed and synthesised to develop inhibitors against α-glucosidase and α-amylase. All the synthesised OA derivatives were evaluated against α-glucosidase and α-amylase in vitro. Among them, compound 3a showed the highest α-glucosid...