Synthesis and bioactivities evaluation of oleanolic acid oxime ester derivatives as α-glucosidase and α-amylase inhibitors

• Hoofdauteurs: Xu-Yang Deng (Auteur), Jun-Jie Ke (Auteur), Ying-Ying Zheng (Auteur), Dong-Li Li (Auteur), Kun Zhang (Auteur), Xi Zheng (Auteur), Jing-Ying Wu (Auteur), Zhuang Xiong (Auteur), Pan-Pan Wu (Auteur), Xue-Tao Xu (Auteur)
• Formaat: Boek
• Gepubliceerd in: Taylor & Francis Group, 2022-12-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Different oleanolic acid (OA) oxime ester derivatives (3a-3t) were designed and synthesised to develop inhibitors against α-glucosidase and α-amylase. All the synthesised OA derivatives were evaluated against α-glucosidase and α-amylase in vitro. Among them, compound 3a showed the highest α-glucosid...