DNA Ministrings: Highly Safe and Effective Gene Delivery Vectors

• Main Authors: Nafiseh Nafissi (Author), Samih Alqawlaq (Author), Eric A Lee (Author), Marianna Foldvari (Author), Paul A Spagnuolo (Author), Roderick A Slavcev (Author)
• Format: Book
• Published: Elsevier, 2014-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Conventional plasmid DNA vectors play a significant role in gene therapy, but they also have considerable limitations: they can elicit adverse immune responses because of bacterial sequences they contain for maintenance and amplification in prokaryotes, their bioavailability is compromised because o...