Pathogenicity and Long-Term Outcomes of Liddle Syndrome Caused by a Nonsense Mutation of SCNN1G in a Chinese Family

• Main Authors: Di Zhang (Author), Yi Qu (Author), Xue-Qi Dong (Author), Yi-Ting Lu (Author), Kun-Qi Yang (Author), Xin-Chang Liu (Author), Peng Fan (Author), Yu-Xiao Hu (Author), Chun-Xue Yang (Author), Ling-Gen Gao (Author), Ya-Xin Liu (Author), Xian-Liang Zhou (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

ObjectiveLiddle syndrome (LS) is a monogenic hypertension consistent with autosomal dominant inheritance, often with early onset high blood pressure in childhood or adolescence. This study aimed to identify the pathogenicity of a nonsense mutation in SCNN1G in a Chinese family with LS and the long-t...