Tumorigenic Cell Reprogramming and Cancer Plasticity: Interplay between Signaling, Microenvironment, and Epigenetics

• Κύριοι συγγραφείς: Vittoria Poli (Συγγραφέας), Luca Fagnocchi (Συγγραφέας), Alessio Zippo (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: Hindawi Limited, 2018-01-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

Accumulating evidences indicate that many tumors rely on subpopulations of cancer stem cells (CSCs) with the ability to propagate malignant clones indefinitely and to produce an overt cancer. Of importance, CSCs seem to be more resistant to the conventional cytotoxic treatments, driving tumor growth...