Machine-Learning Exploration of Exposure-Effect Relationships of Cisplatin in Head and Neck Cancer Patients

• Главные авторы: Céleste Cauvin (Автор), Laurent Bourguignon (Автор), Laure Carriat (Автор), Abel Mence (Автор), Pauline Ghipponi (Автор), Sébastien Salas (Автор), Joseph Ciccolini (Автор)
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• Опубликовано: MDPI AG, 2022-11-01T00:00:00Z.
• Предметы: article
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Background: Cisplatin is a pivotal drug in the treatment of head and neck cancer, and personalized dosage should help the preservation of an optimal toxicity-efficacy ratio. Methods: We analyzed the exposure-effect relationships of 80 adult patients with head and neck cancers and treated with standa...