Pretreatment with Lithospermic Acid Attenuates Oxidative Stress- induced Apoptosis in Bone Marrow-derived Mesenchymal Stem Cells via Anti-oxidation and Activation of PI3K/Akt Pathway

• Main Authors: Li Wang-Yang (Author), Zhou You-Liang (Author), Li Tiao (Author), Zeng Peng (Author), Xu Wu-Ji (Author), Lu Xiao-Long (Author), Qi Xin-Yu (Author), Xiong Hui (Author)
• Format: Book
• Published: KeAi Communications Co., Ltd., 2019-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Despite the potential therapeutic approaches of bone marrow-derived mesenchymal stem cells (BMSCs) in orthopaedic, their applications are hampered by harsh oxidative stress conditions after transplantation. In this study, the anti- apoptotic and anti-oxidative properties of lithospermic a...