Dupilumab normalizes correlates of lysosomal function in atopic dermatitis

• Main Authors: Christina Bürgler (Author), Danielle Dutoit (Author), Susanne Radonjic‐Hoesli (Author), Kathrin Thormann (Author), Mathias Lehmann (Author), Shida Yousefi (Author), Hans‐Uwe Simon (Author), Dagmar Simon (Author)
• Format: Book
• Published: Wiley, 2024-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Atopic dermatitis (AD) is characterized by skin barrier dysfunction and immune dysregulation. Autophagy, which is important for the epidermal differentiation, is impaired in AD. The treatment with dupilumab, an interleukin (IL)‐4/IL‐13 receptor blocker, has been shown to reduce s...