Human radiolabeled mass balance studies supporting the FDA approval of new drugs

• Main Authors: Anuradha Ramamoorthy (Author), Girish Bende (Author), Edwin Chiu Yuen Chow (Author), Hristina Dimova (Author), Neil Hartman (Author), Daphney Jean (Author), Sonia Pahwa (Author), Yunzhao Ren (Author), Chinmay Shukla (Author), Yuching Yang (Author), Suresh Doddapaneni (Author), Zhixia Yan Danielsen (Author)
• Format: Book
• Published: Wiley, 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Human radiolabeled mass balance studies are an important component of the clinical pharmacology programs supporting the development of new investigational drugs. These studies allow for understanding of the absorption, distribution, metabolism, and excretion of the parent drug and metabolit...