Platelet-derived growth factor signaling in pericytes promotes hypothalamic inflammation and obesity

• Main Authors: Akira Okekawa (Author), Tsutomu Wada (Author), Yasuhiro Onogi (Author), Yuki Takeda (Author), Yuichiro Miyazawa (Author), Masakiyo Sasahara (Author), Hiroshi Tsuneki (Author), Toshiyasu Sasaoka (Author)
• Format: Book
• Published: BMC, 2024-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Pericytes are a vital component of the blood-brain barrier, and their involvement in acute inflammation was recently suggested. However, it remains unclear whether pericytes contribute to hypothalamic chronic inflammation and energy metabolism in obesity. The present study invest...