Quantitative receptor model for responses that are left- or right-shifted versus occupancy (are more or less concentration sensitive): the SABRE approach
Simple one-to three-parameter models routinely used to fit typical dose-response curves and calculate EC50 values using the Hill or Clark equation cannot provide the full picture connecting measured response to receptor occupancy, which can be quite complex due to the interplay between partial agoni...
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| Format: | Book |
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Frontiers Media S.A.,
2023-12-01T00:00:00Z.
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Connect to this object online.3rd Floor Main Library
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A1234.567 |
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| Copy 1 | Available |