Synthesis and Evaluation of ^99mTc-Labelled 2-Nitroimidazole Derivatives with Different Linkers for Tumour Hypoxia Imaging

• Päätekijät: Qing Ruan (Tekijä), Yitong Liu (Tekijä), Lihao Liao (Tekijä), Jinyu Hao (Tekijä), Yuhao Jiang (Tekijä), Jianyong Jiang (Tekijä), Junbo Zhang (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: MDPI AG, 2023-09-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

When developing novel radiopharmaceuticals, a linker moiety between the chelator and targeting vector can have a crucial influence on adjusting the affinity of the tracer and its biodistribution in organisms. To develop novel ^99mTc-labelled hypoxia imaging radiotracers, in thi...