PGC-1β modulates catabolism and fiber atrophy in the fasting-response of specific skeletal muscle beds

• Main Authors: Svenia Schmid (Author), Barbara Heim-Kupr (Author), Joaquín Pérez-Schindler (Author), Shivani Mansingh (Author), Markus Beer (Author), Nitish Mittal (Author), Nikolaus Ehrenfeuchter (Author), Christoph Handschin (Author)
• Format: Book
• Published: Elsevier, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Skeletal muscle is a pivotal organ for the coordination of systemic metabolism, constituting one of the largest storage site for glucose, lipids and amino acids. Tight temporal orchestration of protein breakdown in times of fasting has to be balanced with preservation of muscle mass and f...