Oxidative Stress Is Associated with Neuroinflammation in Animal Models of HIV-1 Tat Neurotoxicity

• Asıl Yazarlar: Jean-Pierre Louboutin (Yazar), Lokesh Agrawal (Yazar), Beverly A. S. Reyes (Yazar), Elisabeth J. Van Bockstaele (Yazar), David S. Strayer (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: MDPI AG, 2014-05-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

HIV-1 trans-acting protein Tat, an essential protein for viral replication, is a key mediator of neurotoxicity. If Tat oxidant injury and neurotoxicity have been described, consequent neuroinflammation is less understood. Rat caudate-putamens (CPs) were challenged with Tat, with or without prior rSV...