Dasatinib ameliorates thioacetamide-induced liver fibrosis: modulation of miR-378 and miR-17 and their linked Wnt/β-catenin and TGF-β/smads pathways

Hepatic stellate cells activation (HSCs) plays a crucial role in the pathogenesis of liver fibrosis. Specific microRNAs have been suggested to affect the activation of HSCs via various signalling pathways including TGF-β/smads and Wnt/β-catenin pathways. Dasatinib is a multitarget inhibitor of many...

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Auteurs principaux: Mai A. Zaafan (Auteur), Amr M. Abdelhamid (Auteur)
Format: Livre
Publié: Taylor & Francis Group, 2022-01-01T00:00:00Z.
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