Pramipexole Upregulates Dopamine Receptor D2 and D3 Expression in Rat Striatum

• Main Authors: Naohito Tokunaga (Author), Mohammed Emamussalehin Choudhury (Author), Noriko Nishikawa (Author), Masahiro Nagai (Author), Tomoaki Tujii (Author), Hirotaka Iwaki (Author), Mika Kaneta (Author), Masahiro Nomoto (Author)
• Format: Book
• Published: Elsevier, 2012-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Randomized clinical trials have shown that pramipexole has an antidepressant effect in patients with Parkinson's disease. We investigated the comparative efficacy of pramipexole toward dopamine receptor D2 and D3 expression in rat brain. Groups of rats were treated subacutely with pramipexole (...