Neonatal GLP1R activation limits adult adiposity by durably altering hypothalamic architecture

• Main Authors: Andrea V. Rozo (Author), Daniella A. Babu (Author), PoMan A. Suen (Author), David N. Groff (Author), Randy J. Seeley (Author), Rebecca A. Simmons (Author), Patrick Seale (Author), Rexford S. Ahima (Author), Doris A. Stoffers (Author)
• Format: Book
• Published: Elsevier, 2017-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Adult obesity risk is influenced by alterations to fetal and neonatal environments. Modifying neonatal gut or neurohormone signaling pathways can have negative metabolic consequences in adulthood. Here we characterize the effect of neonatal activation of glucagon like peptide-1 (GLP-1) re...