Rab11 and actin cytoskeleton participate in Giardia lamblia encystation, guiding the specific vesicles to the cyst wall.

• Main Authors: Araceli Castillo-Romero (Author), Gloria Leon-Avila (Author), Ching C Wang (Author), Armando Perez Rangel (Author), Minerva Camacho Nuez (Author), Carlos Garcia Tovar (Author), Jorge Tonatiuh Ayala-Sumuano (Author), Juan Pedro Luna-Arias (Author), Jose Manuel Hernandez (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2010-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Giardia passes through two stages during its life cycle, the trophozoite and the cyst. Cyst formation involves the synthesis of cyst wall proteins (CWPs) and the transport of CWPs into encystation-specific vesicles (ESVs). Active vesicular trafficking is essential for encystation, but the molecular...