Bisphosphonates Targeting Ion Channels and Musculoskeletal Effects

• Main Authors: Rosa Scala (Author), Fatima Maqoud (Author), Marina Antonacci (Author), Jacopo Raffaele Dibenedetto (Author), Maria Grazia Perrone (Author), Antonio Scilimati (Author), Karen Castillo (Author), Ramón Latorre (Author), Diana Conte (Author), Saïd Bendahhou (Author), Domenico Tricarico (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Bisphosphonates (BPs) are the most used bone-specific anti-resorptive agents, often chosen as first-line therapy in several bone diseases characterized by an imbalance between osteoblast-mediated bone production and osteoclast-mediated bone resorption. BPs target the farnesyl pyrophosphate synthase...