Improving the Dissolution Rate and Bioavailability of Curcumin via Co-Crystallization

• Main Authors: Hao Wang (Author), Chenxuan Zheng (Author), Fanyu Tian (Author), Ziyao Xiao (Author), Zhixiong Sun (Author), Liye Lu (Author), Wenjuan Dai (Author), Qi Zhang (Author), Xuefeng Mei (Author)
• Format: Book
• Published: MDPI AG, 2024-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Curcumin (CUR) is a natural polyphenolic compound with various pharmacological activities. Low water solubility and bioavailability limit its clinical application. In this work, to improve the bioavailability of CUR, we prepared a new co-crystal of curcumin and L-carnitine (CUR-L-CN) via liquid-assi...