Improving the Dissolution Rate and Bioavailability of Curcumin via Co-Crystallization

• Автори: Hao Wang (Автор), Chenxuan Zheng (Автор), Fanyu Tian (Автор), Ziyao Xiao (Автор), Zhixiong Sun (Автор), Liye Lu (Автор), Wenjuan Dai (Автор), Qi Zhang (Автор), Xuefeng Mei (Автор)
• Формат: Книга
• Опубліковано: MDPI AG, 2024-04-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Curcumin (CUR) is a natural polyphenolic compound with various pharmacological activities. Low water solubility and bioavailability limit its clinical application. In this work, to improve the bioavailability of CUR, we prepared a new co-crystal of curcumin and L-carnitine (CUR-L-CN) via liquid-assi...