Comparative expression profiling of Leishmania: modulation in gene expression between species and in different host genetic backgrounds.

• Main Authors: Daniel P Depledge (Author), Krystal J Evans (Author), Alasdair C Ivens (Author), Naveed Aziz (Author), Asher Maroof (Author), Paul M Kaye (Author), Deborah F Smith (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2009-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Genome sequencing of Leishmania species that give rise to a range of disease phenotypes in the host has revealed highly conserved gene content and synteny across the genus. Only a small number of genes are differentially distributed between the three species sequenced to date, L. major, L. infantum...