Involvement of oxidative species in cyclosporine-mediated cholestasis

• Váldodahkkit: Bernard Nsengimana (Dahkki), Edozie Samuel Okpara (Dahkki), Wanqing Hou (Dahkki), Chuyun Yan (Dahkki), Shuxin Han (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Frontiers Media S.A., 2022-11-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Cyclosporine is an established medication for the prevention of transplant rejection. However, adverse consequences such as nephrotoxicity, hepatotoxicity, and cholestasis have been associated with prolonged usage. In cyclosporine-induced obstructive and chronic cholestasis, for example, the overpro...