In Vivo Evaluation of a Gastro-Resistant HPMC-Based "Next Generation Enteric" Capsule

• Main Authors: Adrian Rump (Author), Marie-Luise Kromrey (Author), Eberhard Scheuch (Author), Vincent Jannin (Author), Lara Rehenbrock (Author), Mladen Vassilev Tzvetkov (Author), Werner Weitschies (Author), Michael Grimm (Author)
• Format: Book
• Published: MDPI AG, 2022-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Many orally dosed APIs are bioavailable only when formulated as an enteric dosage form to protect them from the harsh environment of the stomach. However, an enteric formulation is often accompanied with a higher development effort in the first place and the potential degradation of fragile APIs dur...