Antibody Profiling in Naïve and Semi-immune Individuals Experimentally Challenged with Plasmodium vivax Sporozoites.

• Main Authors: Myriam Arévalo-Herrera (Author), Mary Lopez-Perez (Author), Emmanuel Dotsey (Author), Aarti Jain (Author), Kelly Rubiano (Author), Philip L Felgner (Author), D Huw Davies (Author), Sócrates Herrera (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2016-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Acquisition of malaria immunity in low transmission areas usually occurs after relatively few exposures to the parasite. A recent Plasmodium vivax experimental challenge trial in malaria naïve and semi-immune volunteers from Colombia showed that all naïve individuals developed malaria symptoms, wh...