In Vitro Activity of a Novel Siderophore-Cephalosporin, GT-1 and Serine-Type β-Lactamase Inhibitor, GT-055, against <i>Escherichia coli</i>, <i>Klebsiella pneumoniae</i> and <i>Acinetobacter</i> spp. Panel Strains

• Asıl Yazarlar: Le Phuong Nguyen (Yazar), Naina Adren Pinto (Yazar), Thao Nguyen Vu (Yazar), Hyunsook Lee (Yazar), Young Lag Cho (Yazar), Jung-Hyun Byun (Yazar), Roshan D'Souza (Yazar), Dongeun Yong (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: MDPI AG, 2020-05-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

This study investigates GT-1 (also known as LCB10-0200), a novel-siderophore cephalosporin, inhibited multidrug-resistant (MDR) Gram-negative pathogen, via a Trojan horse strategy exploiting iron-uptake systems. We investigated GT-1 activity and the role of siderophore uptake systems, and the combin...