LSD1 inhibition suppresses the growth of clear cell renal cell carcinoma via upregulating P21 signaling

• Main Authors: Liangsong Zhu (Author), Jianfeng Wang (Author), Wen Kong (Author), Jiwei Huang (Author), Baijun Dong (Author), Yiran Huang (Author), Wei Xue (Author), Jin Zhang (Author)
• Format: Book
• Published: Elsevier, 2019-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Histone lysine-specific demethylase 1 (LSD1) has been implicated in the disease progression of several types of solid tumors. This study provides the first evidence showing that LSD1 overexpression occurred in 62.6% (224/358) of clear cell renal cell carcinomas (ccRCC). LSD1 expression was associate...