Inactivation of PI3K/Akt promotes the odontoblastic differentiation and suppresses the stemness with autophagic flux in dental pulp cells

• Main Authors: Sam Young Park (Author), Heui Seung Cho (Author), Kyung Hwun Chung (Author), Bin Na Lee (Author), Sun Hun Kim (Author), Won Jae Kim (Author), Ji Yeon Jung (Author)
• Format: Book
• Published: Elsevier, 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background/purpose: Autophagy is involved in controlling differentiation of various cell types. The present study aimed to investigate the mechanism related to autophagy in regulating odontogenic differentiation of dental pulp cells. Materials and methods: Human dental pulp cells (HDPCs) were cultur...